Edition V06N01 | Year 2016 | Editorial Endo in Endo | Pages 11 to 14
Root canal sealers can be made with calcium hydroxide, zinc oxide and eugenol, glass ionomer, resin associated with methacrylate or silicone. They should be subjected to investigation on their potential for genotoxic and mutagenic effects before being launched into the specialized market, since such properties are part of the biocompatibility concept. In the present study, test modalities and the concepts of genotoxicity, mutagenicity and carcinogenesis are highlighted.
Lima NG, Trevizan M, Carvalho FK, Nelson-Filho P, Consolaro A. Can root canal sealers induce cancer? How can we investigate that? Dental Press Endod. 2016 Jan-Apr;6(1):11-4. DOI: http://dx.doi.org/10.14436/2358-2545.6.1.011-014.end