Edition V05N02 | Year 2015 | Editorial Article | Pages 26 to 32
In order to evaluate late biological response of two types of filling material of deciduous teeth, calcium hydroxide and Guedes-Pinto pastes, the implantation technique in rat sockets was employed. For morphological analysis, carried out after 7 and 28 days, 48 rats had their maxillary right central incisor removed, and a polyethylene tube implant containing one of the pastes was placed into the socket. On the 7th day, calcium hydroxide paste caused greater edema than Guedes-Pinto paste, and both types of material showed connective tissue with fibroblasts and blood vessels, with macrophages and lymphocytes. On the 28th day, calcium hydroxide paste had connective tissue with a large amount of macrophages and lymphocytes near the material, whereas in further areas, it had neofomed trabeculae. For the Guedes-Pinto paste, there were neoformed bone trabeculae nearby. The latter were found in larger amounts in areas further from the material surface. Guedes-Pinto paste caused less edema and provided less interference in the repair process.
Takahashi K, Maltempi Filho P, Cunha RF, Dezan Junior E. Evaluation of rat tissue response to Guedes-Pinto and calcium hydroxide pastes by means of morphological analysis of rat’s socket implant. Dental Press Endod. 2015 May-Aug;5(2):26-32. DOI: http://dx.doi.org/10.14436/2358-2545.5.2.026-032.oar